Renal+Pathology

Hyponatremia Hypernatremia Polyuria Edema Diuretics Metabolic Alkalosis Metabolic Acidosis Hyperkalemia Hypokalemia Urinalysis Glomerular Disease Renal Vascular Disease Chronic Renal Failure Acute Renal Failure Tubulointerstitial Disease

Web-based Introduction to Renal Pathology

Objectives

 * describe under what conditions renal biopsies are necessary
 * Know the anatomical and histological structures of the kidney, and the results of pathological change in each one
 * Describe the use of immunofluorescence microscopy and electron microscopy in renal pathology
 * explain why common histological stains and methods are inadequate in renal pathology
 * Understand what changes in urine chemistry accompany common renal pathologies.

Urinalysis Lab – with focus as indicated in the Introduction to the lab

02Glomerular Filtration/Gadegbeku

05,06 Proteinuria and Non‑Inflammatory Diseases of the Glomerulus/Holzman,Killen

07Nephrotic Syndrome CPC >* Normal Kidney, pp956-959 >* Nephrotic Syndrome, pp978-984 >* Diabetic Nephrosclerosis, pp990-992
 * Reading: Robbins & Coltran:

08 The Kidney and Systemic Disease-Diabetes/Brosius

09 Glomerulonephritis and Nephritic Syndromes/Holzman, Killen Nephritic Syndrome CPC Acute Glomerulonephritis-pp. 973-976   Rapidly Progressive Glomerulonephritis-pp. 976-978   IgA Nephropathy-pp. 986-988   Systemic Lupus Erythematosus-pp. 227-235
 * Robbins Pathologic Basis of Disease; 7th Edition.:**

19 The Kidney and Hypertension/Young

24Calcium and Phosphorus Metabolism/Young

20Inherited Disorders of the Kidney/Killen
 * Robbins Pathologic Basis of Disease; 7th Edition**
 * Cystic diseases of the kidney: pp. 962-966, Table 20-2.
 * Hereditary nephritis: pp. 998-989.

Symposium on Chronic Renal Failure/Saran, Rao

21,22 Mechanisms of Acute Renal Failure and Approach to the Patient with Acute Renal Failure/Weinberg

31Tubulointerstitial Disease/Johnson Renal Failure Pathology Lab A. Acute Tubular Necrosis and Acute Renal Failure; pp. 993-996 B. Tubulointerstitial Diseases: * Pyelonephritis; pp. 996-1002 * Drug Induced Interstitial Nephritis; pp. 1002-1004 * Multiple Myeloma and the Kidney; pp. 1005-1006
 * Robbins Pathologic Basis of Disease; 7th Edition:**

28-30Transplantation‑Immunosuppression/Cibrik,Norman,Magee

34Lower Urinary Tract/Latini,Shah

32 Prostate Pathology/Lee,Shah

36-38Pathology of the Kidney and Upper Urinary Tract/Weizer GU Pathology CPC

Goals
-Renal Neoplasia, pp. 1015-1019. -Urothelial Neoplasia, pp. 1028-1033. -Prostate Hyperplasia and Neoplasia, pp. 1047-1057.
 * know the common gross and microscopic description of renal cell carcinoma
 * know the grading of renal epithelial neoplasia
 * Know the patterns of papillary, in situ, and invasive transitional carcinoma, and the clinical history of each
 * Know the clinical manifestations of prostate neoplasia and hyperplasia
 * Robbins Pathologic Basis of Disease; 7th Edition:**

Small Groups ‑ Renal Disease Cases

Killen Pathology Review