CNS+Infection

neurlogical infections Meningitis bacterial most important form of meningitis photophobia,

brudzinski's hip flexsion nprecipitated by neck flexion Kernig's=ain on extension of knee while hip flexed

bring up knee, complain of pain on knee les specific meninges swollen need a way to remember gross patholgoy has a bad cold without a box of cleenex

inflammatory products. vascular permeability->edema

high white count high protein low glucose implies bacterial meningitis treat with antibiotics...dexamethasone...

viral...less wecan do about it make sure not bacterial

infiltration... clincial fever, headache, mental status change path: finlammation pathosphysiology

fungal...eww can sit for months or years

more indolent course ell count may go higher still lymphocytic predominance

wbcs...can be higher...

crytpococcus histoplasma blastomycis coccidioides...wouthwest Candida...brun pts, TPN aspergillus mucurmycosis...dabeteics paracoccidiodies...central, south america

Treatment: amphotericin B Flycutosine during initial therapy..in AIDs pts FLuconazole maintenance therapy in aids pts

TB meningitis... several week prodrome gradual headache

blood vessels near circle of willis granuloma center... caseating...cheese like

brain parenchyma

VZV shingles