Opioid+Drugs

toc =Definitions= Opioid Opiate Narcotic Opiopeptin

=Mechanism= Receptors

=Tolerance=

Withdrawal
=Opioid Agonist: Morphine Sulfate (MS)=

Respiratory Depression

 * Increased ICP**

Other Side Effects

 * Pneumonia
 * Sedation
 * biliary or urinary spasm
 * Prolonged labor
 * Dependence

Interactions
=Other Opioid Agonists= =Weak Opioid Agonists=
 * **Other CNS Depressants!**
 * Antipsychotics and sedative antidepressants potentiate sedation
 * MAO interaction

Diphenoxylate/atropine (Lomotil) and Loperamide (Immodium)
=Mixed Agonists/Antagonists=

Nalpuphine, Buprenorphine, Butorphanoll, Dezocine
=Opioid Antagonists=

Naloxone, Naltrexone
=Antitussives=